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the effect of tranexamic acid in prevention of extracted tooth dry socket

Evaluation of Effect of Biodegradable Dressing Loading Tranexamic Acid in Prevention of Alveolar Osteitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140503017537N5
Enrollment
180
Registered
2018-03-09
Start date
2017-09-23
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar osteitis. Alveolitis of jaws

Interventions

Intervention 1: Intervention group: A biodegradable dressing is placed in the sockets of the extracted teeth, which are loaded with tranexamic acid for the study group. Intervention 2: Control group:

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients in need of surgical extraction of the mandibular third molar who refer to oral surgery department of Kermanshah dental school Patients with risk factors for alveolar osteitis (history of pericoronitis, smoking, use of OCPs, history of alveolar osteitis)

Exclusion criteria

Exclusion criteria: Hypersensitivity to tranexamic acid Prohibition of prescription of tranexamic acid by patients' physician Antibiotic therapy regimen Surgical complications in surgeon's opinion Patients' unwillingness to cooperate with the trial Loss to follow up

Design outcomes

Primary

MeasureTime frame
Incidence of alveolar osteitis after surgical extraction of mandibular impacted third molars. Timepoint: 3rd and 7th days after surgery. Method of measurement: Clinical diagnosis of the disease by an experienced oral and maxillofacial surgeon regarding the signs and symptoms including: pain, halitosis, exposed alveolar bone, presence of no or insufficient blood clot in the socket.

Secondary

MeasureTime frame
Pain intensity after surgery. Timepoint: 3rd and 7th days after surgery. Method of measurement: Using Visual Analogue Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHesamedin Nazari

Kermanshah University of Medical Sciences

H.nazari@kums.ac.ir+98 83 3729 6591

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026