Evaluation of the administration of betamethasone on late preterm labor and its outcomes.

Betamethasone effect of pregnancy on neonatal outcomes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014050217365N2

Enrollment

200

Registered

2015-05-05

Start date

2015-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Neonatal respiratory distress syndrome. Condition 2: Preterm Labor. Hyaline Membrane Disease Onset (Spontaneous) of Labor Before 37 Completed Weeks of Gestation

Interventions

Intervention 1: Intervention group: intramuscular injection of 48 mg of betamethasone solution (4 ampoules 12 mg) divided in two doses within 24 hours. Pharmaceutical Company LLP, Iran registration nu

Treatment - Drugs

Intervention group: intramuscular injection of 48 mg of betamethasone solution (4 ampoules 12 mg) divided in two doses within 24 hours. Pharmaceutical Company LLP, Iran registration number 1228030994.

Control group: no injection of betamethasone

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Pregnant women who are candidate for delivery in 34-37th week of gestational age based on LMP or Ultrasound before 20 weeks of gestation; The informed consent of the method of treatment. Exclusion criteria: Multiple pregnancies; major congenital malformations; hemorrhagic syndromes active major bleeding; clinical evidence of chorioamnionitis, previous use of corticosteroids; the need for quick termination of pregnancy by the mother or fetus; insulin-dependent diabetes; smoking and drugs by the mother; contraindications of corticosteroids.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Respiratory distress syndrome in the baby after birth. Timepoint: Every half hour until 48 hours after birth. Method of measurement: Questionnaire.;Apgar score. Timepoint: At Birth. Method of measurement: Questionnaire.;Kind of delivery. Timepoint: At Birth. Method of measurement: Questionnaire.;The need for hospitalization. Timepoint: After Birth. Method of measurement: Questionnaire.	—

Secondary

Measure	Time frame
Gestational age at birth. Timepoint: After birth. Method of measurement: Questionnaire.;Infant death. Timepoint: At Birth. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahadoriFatemeh

Urmia university of medical sciences

fbahadory27@yahoo.com+98 44 3223 7077

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026