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Comparison of calcium and calcium placebo pre-rinse effect on salivary and plaque fluoride and calcium concentrations after the use of 900 ppm sodium fluoride mouthwash

Comparison of calcium and calcium placebo pre-rinse effect on salivary and plaque fluoride and calcium concentrations after the use of 900 ppm sodium fluoride mouthwash

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201404286105N3
Enrollment
30
Registered
2014-06-01
Start date
2014-01-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries. Other infectious diseases

Interventions

Intervention 1: Intervention 1: 160 mmol/l calcium lactate mouthwash (Merk, Germany), 10 ml of mouth wash will be rinsed for 1 minutes. Immediately after that, 0.2% NaF mouthwash (Behsa, Iran), 10 ml
Prevention
Placebo
Intervention 1: 160 mmol/l calcium lactate mouthwash (Merk, Germany), 10 ml of mouth wash will be rinsed for 1 minutes. Immediately after that, 0.2% NaF mouthwash (Behsa, Iran), 10 ml of mouth wash w
Intervention 2: Distilled water mouthwash (Iran,), 10 ml of mouth wash will be rinsed for 1 minutes. Immediately after that, 0.2% NaF mouthwash (Behsa, Iran), 10 ml of mouth wash will be rinsed for 1

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 24 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Good oral hygiene which was checked clinically by the absence of food debris and plaque accumulations; having at least 24 natural teeth; normal unstimulated whole saliva flow rate (0.25-0.35 ml/min); good oral (no demineralized enamel, no congenital enamel anomaly, no untreated decay, no faulty dental restorations) and general health Exclusion criteria: Dentures and orthodontic appliances; Medications for at least 4 weeks before the project started.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Salivary calcium concentration. Timepoint: 1 and 12 hours after intervention 1 and 2. Method of measurement: by spectrophotometry.;Salivary fluoride concentration. Timepoint: 1 and 12 hours after intervention 1 and 2. Method of measurement: using fluoride selective electrode.;Dental plaque fluoride concentration. Timepoint: 1 and 12 hours after intervention 1 and 2. Method of measurement: using fluoride selective electrode.;Dental plaque calcium concentration. Timepoint: 1 and 12 hours after intervention 1 and 2. Method of measurement: by spectrophotometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNahid Ramazani

Zahedan University of Medical Sciences

ramazani_nahid@yahoo.com+98 54 1242 3218

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026