Compression methods of pain relief during infiltration injection anesthesia for maxillary central incisors

The effect of mucosal cooling and topical anesthesia application on pain perception during infiltration injection and latency time of anesthesia for maxillary central incisors

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014042817477N1

Enrollment

Registered

2014-06-28

Start date

2014-05-05

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain of needle insertion and injection during buccal infiltration and latency time of anesthesia for maxillary central incisors.

Interventions

Intervention 1: Useing topical anesthesia at the injection site before infiltration of local anesthetics in the buccal mucosa for 1 minute. Intervention 2: Cooling the injection site before infiltrati

Treatment - Other

Useing topical anesthesia at the injection site before infiltration of local anesthetics in the buccal mucosa for 1 minute

Cooling the injection site before infiltration of local anesthetics in the buccal mucosa for 5 seconds

Without use topical anesthesia and cooling at the injection site before infiltration of local anesthetics in the buccal mucosa

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The inclusion criteria: healthy volunteers (ASA I) who had intact maxillary central incisors that responded to an electric pulp tester and had no tenderness to palpation and percussion and no advanced periodontal disease; ability to understand the use of pain scales; no toxic habits (including alcohol abuse, smoking or regular cannabis smoking or other drug use); absence of acute or chronic infections in the oral and maxillofacial area. The exclusion criteria: those had taken opioid, nonopioid analgesics, steroids, antidepressants or sedatives within 48 h before the study; those who were pregnant; those incapable of giving informed consent; patients with known allergies to lidocaine or to epinephrine; those with peripheral neuropathy; those reporting specific phobia related to dental settings or history of traumatic dental injury.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain during insertion and injection local anesthesia. Timepoint: During insertion and injection local anesthesia. Method of measurement: Heft Parker Visual Analog Scale.	—

Secondary

Measure	Time frame
Assess the time elapsed between the injection and no response to pulp testing. Timepoint: Two minutes interval after anesthesia infiltration. Method of measurement: Respond to electric pulp tester.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeede Sadr

Hormozgan University of Medical Sciences

saeede.sadr@hums.ac.ir+98 76 1335 0256

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026