Liver Transaminase elevation. nonspecific elevation of Transaminase and Lactic Acid Dehydrogenase
Conditions
Interventions
Intervention 1: Intervention Group: Vitamin E capsule,oral, 400 unit daily,for 30 days. Intervention 2: Control group:placebo capsule,similar to Vit E capsule,one capsule per day for 30 days.
Treatment - Drugs
Placebo
Intervention Group: Vitamin E capsule,oral, 400 unit daily,for 30 days
Control group:placebo capsule,similar to Vit E capsule,one capsule per day for 30 days
Sponsors
Vice Chancellor for Medical Sciences research of Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria:l Patients with elevated Liver Transaminase levels induced by Atorvastatin Use at level of 1.5 to 3 times more than its baseline levels. Exclusion criteria:Patients who had received other medications with effect on elevation of Liver Transaminase levels;patients who had history of Liver disease or elevated Liver Transaminase levels before Atorvastatin use.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver Transaminases. Timepoint: One week befor intervention and one day after intervention. Method of measurement: Unit in dl. | — |
Secondary
| Measure | Time frame |
|---|---|
| Vomiting,Neusea. Timepoint: Two weeks after intervention. Method of measurement: yes or no. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Kamran Agha Sadeghi
Shiraz, Univercity of Medica Sciences ,Cardio Vascular research center
Outcome results
None listed