COVID-19. covid-19, virus identified
Conditions
Interventions
Intervention group: All people receiving health care services from PIHO residing in Fars, Hormozgan, and Ahwaz centers. The intervention group individuals will receive 4 drops of OPV vaccine (provided
Sponsors
Petroleum Industry Health Organization
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All people receiving health care services from PIHO in the three provinces who agree to participate in the study (Fars, Hormozgan and Khuzestan).
Exclusion criteria
Exclusion criteria: All those with contraindication to receive OPV including immunocompromised people and those living with an immunocompromised person (including those with active malignancy receiving chemo/radiation therapy, transplant recipients receiving immunosuppressant drugs, those with active HIV infection, and those with congenital immunodeficiency). Those with severe flu, high-grade fever, and history of allergy to other vaccines will be excluded too. We will also exclude those who have newborn children who may be yet unimmunized against polio.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The age-adjusted incidence of COVID-19 in vaccinated people compared with that in unvaccinated general population (aRR). Timepoint: 2 months after vaccination. Method of measurement: daily count of new patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| The aged-adjusted incidence of vaccine-related side effects in vaccinated people compared with that in unvaccinated general population. Timepoint: 2-3 months after vaccination. Method of measurement: Counting those who may have side-effects.;To assess the age-adjusted mortality rate from COVID-19 in vaccinated people compared with that in unvaccinated general population. Timepoint: 2-3 months after vaccination. Method of measurement: Counting dead people.;To assess the disease severity in those with COVID-19 in vaccinated and unvaccinated people. Timepoint: 2-3 months after vaccination. Method of measurement: Assessed by the 8-point scale used by NIH. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarrokh Habibzadeh
Petroleum Industry Health Organization
Outcome results
None listed