Evaluating the effect of L-carnitine on CK-MB and troponin T value following coronery artery bypass grafting (CABG) surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201404268698N13

Enrollment

100

Registered

2014-06-12

Start date

2013-08-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerotic heart disease. Atherosclerotic heart disease

Interventions

Intervention 1: Intervention group: administration of L-carnitine, 1 g oral solution vial, 3 times a day (TDS) every 8 hours, duration of intervention is 4 days (from 48 hours before surgery until 48

Treatment - Drugs

Intervention group: administration of L-carnitine, 1 g oral solution vial, 3 times a day (TDS) every 8 hours, duration of intervention is 4 days (from 48 hours before surgery until 48 hours after it)

Control group: This group does not receive any interventions

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patients who candidate for Coronary artery bypass graft surgery in Tehran Heart center are selected by simple randomised method; There are not any limitations for age; and sex in this study. Exclusion criteria: Valvular surgery; History of supraventricular arrhythmia; History of siezure; History of hypersensitivity reaction to l-carnitine; Chronic liver failure (Liver enzymes more than 3 times of ULN); Chronic kidney disease (Stage IV & V); Hypothyroidism; Use of Magnesium, NSAIDs and Antiarrhythmic medication, history of myocardial infarction within 1 month of hospitalization

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Atrial fibrillation. Timepoint: 5 days post CABG surgery. Method of measurement: ECG, CK-MB.	—

Secondary

Measure	Time frame
Atrial fibrillation. Timepoint: 5 days post CABG surgery. Method of measurement: Troponin T.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzita Hajhossein Talasaz

Tehran University of Medical Sciences

atalasaz@razi.tums.ac.ir+98 21 6695 4709

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026