Brucellosis. Brucellosis due to Brucella melitensis
Conditions
Interventions
Intervention 1: Control group :Adminisration Gentamicin 4-5 mg / kg (IM) for a week, Doxcycycline 100 mg/bid (oral) for 45 days. Intervention 2: Intervention group: Adminisration Gentamicin 4-5 mg
Treatment - Drugs
Control group :Adminisration Gentamicin 4-5 mg / kg (IM) for a week, Doxcycycline 100 mg/bid (oral) for 45 days
Intervention group: Adminisration Gentamicin 4-5 mg / kg (IM) for a week, Doxcycycline 100 mg/bid ( oral) for 45 days and levamisole 80 mg( oral )daily for 6 weeks.
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
All
Age
8 Years to 139 Years
Inclusion criteria
Inclusion criteria: After providing adequate information eligible patients volenteer will be enrolled in the study. Inclusion criteria: the patient had not received treatment, and also clinical signs and para clinical signs including, blood cultures, Wright test, 2ME and combs wright. Exclusion criteria: pregnant women; children younger than 8 years old; endocarditis, meningitis and spondylitis patients.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantity of regulatory T cells. Timepoint: Before treatment,6 weeks after begining of treatment,6months after end of treatment. Method of measurement: Flow cytometric.;Brucella bacteria. Timepoint: Before treatment,6 weeks after begining of treatment,6months after end of treatment. Method of measurement: Blood culture.;??Antibody of serum. Timepoint: Before treatment,6 weeks after begining of treatment,6months after end of treatment. Method of measurement: Wright test,2ME,Coombs. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Reza Hasanjani Roshan
Babol University of Medical Sciences
Outcome results
None listed