Improvement in Pulmonary parameters in patients during and after coronary bypass surgery

Comparison between continuous lung ventilation at low minute volume and non-ventilation during ?pumping in oxygenation and extubation in patients undergoing coronary bypass surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014042513159N4

Enrollment

Registered

2014-05-17

Start date

2014-06-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary heart disease. Pulmonary heart disease, unspecified

Interventions

Intervention 1: Intervention group: patients with continuous ventilation of the lungs with low minute volume, with a tidal volume of 4 ml/ kg and a respiratory rate of 12 per minute during cardiopulmo

Treatment - Other

Intervention group: patients with continuous ventilation of the lungs with low minute volume, with a tidal volume of 4 ml/ kg and a respiratory rate of 12 per minute during cardiopulmonary bypass pump

Control group: Patients without ventilation, after connecting to cardiopulmonary bypass pump, oxygen and ventilation are disconnected and oxygenation of the patient's blood occurs through a bypass pu

Eligibility

Sex/Gender

All

Age

45 Years to 75 Years

Inclusion criteria

Inclusion criteria: The main inclusion criteria: Male and female candidates for elective coronary artery bypass surgery; ?Consent to participate in the study; The age range of 40-75 years; Body mass index (BMI)) less than 30.? The main exclusion criteria: Underlying lung disease; Previous history of diabetes; Pulmonary blood ?pressure; Grade 2 (or higher) diastolic dysfunction; previous history of surgery or CABG surgery; ?Ejection fraction (EF) less than 30%; Pumping time more than 2 hours; Long ventricular fibrillation or ?prolonged heart massage during surgery; Other factors causing prolonged ventilation.?

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Oxygen Pressure in arterial blood. Timepoint: Before, During and after anesthesia. Method of measurement: Arterial blood test.;Fraction of Inspired Oxygen. Timepoint: Before, during and after anesthesia. Method of measurement: Arterial blood test.	—

Secondary

Measure	Time frame
Point atelectasis. Timepoint: In ICU after intervention. Method of measurement: Chest radiograph.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShima Sheybani

Mashhad University of Medical Sciences

sheybanish@mums.ac.ir+98 51 1801 2612

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026