Anemia in patients with hemodialysis. Chronic kidney disease
Conditions
Interventions
Intervention 1: case group:400 mg of pentoxifylline daily for 4 months. Intervention 2: control group: 1 placebo tablet daily.
Treatment - Drugs
Placebo
case group:400 mg of pentoxifylline daily for 4 months
control group: 1 placebo tablet daily
Sponsors
Vice-chancellor for research -Shahid Sadoughi University of Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: all patients with chronic hemodialysis who had hemoglobin level less than 11 gr/dL despite receiving 100-200 IU/Kg/W recombinant erythropoietin at least 3 months before starting the study. Exclusion criteria: age 300 pg/mL; Iron deficiency ( ferritin level < 100 µg/L or TIBC < 20% ); any hospitalization in past month ; the previous history of hematological problems such as hemoglobinopathies.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean changes in hemoglobin concentrations. Timepoint: 4 times, monthly. Method of measurement: with CBC. | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythrocyte Sedimentation Rate. Timepoint: each 2 months. Method of measurement: with lab tests.;C Reactive Protein. Timepoint: each 2 months. Method of measurement: with lab tests. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mohsen Gholinataj
Shahid Sadoughi University of Medical Sciences
Outcome results
None listed