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Efficacy of green tea extract in the treatment of the patients with dry eye.

Comparing the effect of green tea extract and artificial tear in control of clinical symptoms, tear production, tear film stability, health of ocular surface and meibomian gland in the patients with dry eye and meibomian gland dysfunction.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014042117374N1
Enrollment
60
Registered
2016-10-03
Start date
2014-05-15
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye. Diseases of the eye and adnexa

Interventions

Intervention 1: Intervention group: Artificial tear eye drop, one drop, three times a day for one month+ Green tea eye drop, one drop, three times a day for one month. For preparation of green tea dr
Treatment - Drugs
Intervention group: Artificial tear eye drop, one drop, three times a day for one month+ Green tea eye drop, one drop, three times a day for one month. For preparation of green tea drop, we brewed g
Control group: Standard treatment include artificial tear eye drop one drop three times a day for one month.

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Incliusion criteria included? Dry eye and meibomian gland dysfunction. Exclusion criteria included? Use of oral tetracyclines and corticosteroids in 3 months before study and all ophthalmic medication in one month before, Patients with other ocular surface disorders such as corneal surface damage, eyelid complications except blepharitis, any previous ocular surgery, history of drug allergy in eye , use of ophthalmic medication to treat other ophthalmic complication except dry eye and blepharitis, severe belepharitis and dry eye that require systemic treatment, Nasolacrimal duct system disorders such as punctal occlusion, Pregnancy and lactation, as well as patients taking systemic medications and systemic diseases affecting this study are excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Clinical symptom. Timepoint: Before the intervention, one month after the intervention. Method of measurement: The questionnaire included: symptoms of itching, Burning, Reduced vision, Foreign body sensation, Pains, photophobia, Redness.;Tear production. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Shirmer test.;Tear film stability. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Tear Film Brake Up Time test.;Ocular surface health. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Staining of the cornea and conjunctiva.;Meibomian glangd safety. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Color and quality of gland secretion.

Secondary

MeasureTime frame
Drug allergy. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Clinical symptom.;Eye infection. Timepoint: Before the intervention, one month after the intervention. Method of measurement: Clinical symptom.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Zadmehr

Shiraz University of Medical Sciences

vcrdep@sums.ac.ir+98 711230541019

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026