Skip to content

Cefazolin injection in off-pump CABG

Prophylactic effect of bolus and continuous Cefazolin injection in off-pump CABG

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014041917026N1
Enrollment
141
Registered
2014-04-19
Start date
2012-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection after cardiac surgery. Other staphylococcus as the cause of diseases classified to other chapters,Staphylococcus aureus as the cause of diseases classified to other chapters

Interventions

Intervention 1: In Bolus group, for patients undergoing Off- Pump Coronary Artery Bypass Graft surgery. Patients in this group received 2g of Cefazolin as a starting dose, 30 minutes before incision.
Prevention
In Bolus group, for patients undergoing Off- Pump Coronary Artery Bypass Graft surgery. Patients in this group received 2g of Cefazolin as a starting dose, 30 minutes before incision. Then 1g of Cefaz
In continuous group, for patients undergoing Off- Pump Coronary Artery Bypass Graft surgery. Patients in this group received 2g of Cefazolin as a starting dose, 30 minutes before incision. Then 3g of

Sponsors

Shahid sadoughi university of medical science, Yazd
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients without history of antibiotic therapy during the last 72 hours before surgery; no severe renal and liver failure and pregnancy; no active infection. Exclusion criteria: all patients didn't consent to use this procedure in the study. we can't use full dose of cefazolin and excise of sign of infection during administering antibiotic.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Infection. Timepoint: One month. Method of measurement: Clinical evidence and paraclinical lab.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Khalil Forouzannia

Shahid Sadoughi University of Medical Sciences, Yazd, Iran

drforouzan_nia@yahoo.com+98 35 1523 1421

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026