Effects of gabapentin on postoperative pain. Postprocedural disorder of genitourinary system, unspecified
Conditions
Interventions
Intervention 1: 1 hour before induction of anesthesia 1 capsules of gabapentin (300mg) were given to patient by a physician. Intervention 2: in control group 1 capsules of placebo similar in shape and
Treatment - Drugs
1 hour before induction of anesthesia 1 capsules of gabapentin (300mg) were given to patient by a physician
in control group 1 capsules of placebo similar in shape and size with true drug were given to patient 1 hour before operation by a physician
Sponsors
Shahid Beheshti University of Medical Science
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: All patients whom were candidate for abdominal hysterectomy assessed for eligibility to enter the study. The inclusion criteria: ASA class I and II; nonmalignant status (benign gynecologic disease); general anesthesia; body mass index (BMI) of 20 to 30 kg/m2 The exclusion criteria: known allergy against gabapentin; epilepsy; motion sickness; previous treatment with gabapentin; chronic pain syndrome; psychiatric disorder and substance abuse; patients who had received analgesics within 48 hours before surgery; duration of surgery excess 3 hours; trauma of urinary system or bowel within surgery
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain. Timepoint: 1 - 4 -8 -12 -24 hours post operation. Method of measurement: questionare, VAS score.;Postoperative nausea and vomiting. Timepoint: within 24 hours post hysterectomy. Method of measurement: questionare. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects of gabapentin. Timepoint: within 24 hours post hysterectomy. Method of measurement: Patient complanit and physical exam. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLeila Nazari
Shahid Beheshti University of Medical Science
Outcome results
None listed