Evaluation of effects of rapid infusion of normal saline during vessel anastomosis on graft function and acid base balance in kidney transplantation surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014041516415N1

Enrollment

Registered

2014-04-15

Start date

2014-03-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease, stage 5. Chronic uraemia End stage kidney disease: in allograft failure NOS on dialysis without dialysis or transplant

Interventions

Intervention: Rapid infusion of normal saline during vessel anastomosis Control: none.

Treatment - Other

Intervention: Rapid infusion of normal saline during vessel anastomosis Control: none

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18-65 years old; end stage renal disease; candidate of elective live donor kidney transplantation; no previous kidney transplantation; no liver disease; ejection fraction more than 45%; ASA I and II Exclusion criteria: Bleeding more than 3 ml/kg; vascular anomaly in donor kidney

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Anion Gap. Timepoint: Before and after fluid infusion. Method of measurement: Calculation of anion gap by measuring blood gas analysis and and blood electrolytes concentration.	—

Secondary

Measure	Time frame
Electrolyte concentration, urine output, blood creatinine concentration. Timepoint: Before and after fluid infusion, 24 and 48 hours after surgery. Method of measurement: Blood sampling and urine collection.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHashemi Mozaffar MD

St Alzahra Hospital

mozafarhashemi@med.mui.ac.ir+98 31 1624 9031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026