Effect of Training and Green Tea Extract on Middle-Aged Obese Men

The effect of High-Intensity Interval Training and High-Intensity Resistance Training with Green Tea Extract on Adipsin, Neuroregulin 4, Asprosin, and Leptin in Middle-Aged Obese Men

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140415017288N13

Enrollment

Registered

2025-04-23

Start date

2025-05-10

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Middle-Aged Obese Men. E66.0

Interventions

Intervention 1: Placebo group: This group receives two 150 mg starch capsules as a placebo during the intervention period. Intervention 2: Intervention group 1: Green tea extract group: This group rec

Eligibility

Sex/Gender

Male

Age

30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Being obese (Body mass index above 30). Age range 30-50 years. Inactive lifestyle (exercise less than 1 hour per week) Being willing to participate in the study.

Exclusion criteria

Exclusion criteria: Diagnosis of other underlying diseases. Allergy to supplement use. Inability to do exercise training. Use of anti-inflammatory drugs.

Design outcomes

Primary

Measure	Time frame
Adipsin. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Neuroregulin 4. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Asprosin. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Leptin. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Insulin resistance index (HOMA-IR). Timepoint: Before and after the protocol. Method of measurement: Biochemical, laboratory and formula methods.;Lipid profile. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Malondialdehyde. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Glutathione peroxidase. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.	—

Measure

Time frame

Adipsin. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Neuroregulin 4. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Asprosin. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Leptin. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Insulin resistance index (HOMA-IR). Timepoint: Before and after the protocol. Method of measurement: Biochemical, laboratory and formula methods.;Lipid profile. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Malondialdehyde. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Glutathione peroxidase. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Abdi

Islamic Azad University

a.abdi@iauamol.ac.ir+98 11 4321 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026