Effect of Training and Resveratrol on Middle-Aged Obese Women

The Effect of Pilates Training with Resveratrol on Serum Levels of Inflammatory Indices, Oxidative Stress and Endoplasmic Reticulum Stress in Middle-Aged Obese Women

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140415017288N11

Enrollment

Registered

2023-03-13

Start date

2023-04-09

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Middle-Aged Obese Women. Obesity due to excess calories

Interventions

Intervention 1: Control group: This group receives a 500 mg starch tablets as a placebo during the 8-week intervention period. Intervention 2: Intervention group 1: Training group (in this group for e

Eligibility

Sex/Gender

Female

Age

35 Years to 50 Years

Inclusion criteria

Inclusion criteria: Being obese (Body mass index above 30). Age range 35-50 years. Inactive lifestyle (exercise less than 1 hour per week) Being willing to participate in the study.

Exclusion criteria

Exclusion criteria: Diagnosis of other underlying diseases. Allergy to supplement use. Inability to do exercise training. Use of anti-inflammatory drugs.

Design outcomes

Primary

Measure	Time frame
Glucose-Regulated Protein 78 (GRP78). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Tribbles homologue 3 (TRB3). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Sestrin-2. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Lipocalin-2 (LCN2). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Malondialdehyde (MDA). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Glutathione peroxidase (GPx). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Insulin resistance index (HOMA-IR). Timepoint: Before and after the protocol. Method of measurement: Biochemical, laboratory and formula methods.	—

Measure

Time frame

Glucose-Regulated Protein 78 (GRP78). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Tribbles homologue 3 (TRB3). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Sestrin-2. Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Lipocalin-2 (LCN2). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Malondialdehyde (MDA). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Glutathione peroxidase (GPx). Timepoint: Before and after the protocol. Method of measurement: Biochemical and laboratory methods.;Insulin resistance index (HOMA-IR). Timepoint: Before and after the protocol. Method of measurement: Biochemical, laboratory and formula methods.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Abdi

Islamic Azad University

a.abdi@iauamol.ac.ir+98 11 4321 7124

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026