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Efficacy of Intravenous erythropoietin in patients with spinal cord injury

Comparison of the efficacy of erythropoietin and methyl prednisolone in improving muscle strength or sensory level outcomes in patients with spinal cord injury.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014041417272N1
Enrollment
60
Registered
2014-07-04
Start date
2013-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal cord injury. G95.2 ?????? ????? ?????

Interventions

Intervention 1: Methylprednisolone 33mg/kg were referred to as bullous within fifteen minutes then 5.4mg/kg methylprednisolone infusion within 23-47 hours. Intervention 2: Intervention group.First Met
Treatment - Drugs
Methylprednisolone 33mg/kg were referred to as bullous within fifteen minutes then 5.4mg/kg methylprednisolone infusion within 23-47 hours.
Intervention group.First Methylprednisolone 33mg/kg were referred to as bullous within fifteen minutes then 5.4mg/kg methylprednisolone infusion within 23-47 hours. then Erythropoietin 500 units per k

Sponsors

Tabriz University of Medical Sciences, MediCenter for Neuroscience Research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Patients who develop symptoms of spinal cord injury and decrease muscle strength or sensory level deficit Frankel classification A - E Exclusion criteria: Patients with uncontrolled hypertension, patients allergic to human albumin, Pregnancy and lactation, erythroid leukemia, Patients with a history of thromboembolic events. in patients with severe coronary artery disease , peripheral arteries, the carotid"brain,brain-damaged patients with low GCS due to lack of accurate sensory, motor cases

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The muscle strength scoring Franklin A-E. Timepoint: Admission, fourth day of admission, the eighth day of admission. Method of measurement: Examination by resident Brain surgery.;The sensory strength scoring Franklin A-E. Timepoint: Admission, fourth day of admission, the eighth day of admission. Method of measurement: Examination by resident Brain surgery.

Secondary

MeasureTime frame
The level of enzyme levels, total Antioxidant capacity. Timepoint: Admission, Fourth day of admission, Eight day of admission. Method of measurement: Kerry measured by enzymatic kits for lab.;The level of enzyme levels, Malon dy Aldehid. Timepoint: Admission, Fourth day of admission, Eight day of admission. Method of measurement: Kerry measured by enzymatic kits for lab.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasrin Pourhajshokr

Tabriz University of Medical Sciences

nasrinpour2000@yahoo.com+98 41 1334 7054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026