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Evaluation of Interleukin 18 in Chronic periodontitis

Evaluation of Interleukin 18 levels in saliva of patients with generalized Chronic periodontitis before and after Scaling and root planing

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201404133795N2
Enrollment
50
Registered
2014-06-23
Start date
2013-04-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: The intervention group: Scaling and root planning. Intervention 2: The control group : observation.
Treatment - Other
The intervention group: Scaling and root planning
The control group : observation

Sponsors

Ahvaz Jundishapour University of Medical Sciences and Health Services
Lead Sponsor

Eligibility

Sex/Gender
All
Age
63 Years to 43 Years

Inclusion criteria

Inclusion criteria: Inclusin criteria: patients with severe periodontitis; patients with moderate to severe periodontitis; subjects with periodontal healthy Exclusion criteria: periodontal treatment or antibiotic therapy within the last 3 months; presence of any systemic disease (e.g.,diabetes mellitus, asthma); xerostomia or any other disease of the salivary glands; less than 20 teeth remaining; intake of any drug known to alter salivary rate levels (e.g., for sleeping disorders) or to be immunosuppressive; usage of partial or total prosthesis; pregnancy; lactation; acute infection; immunodeficiency; history of radio- or chemotherapy; and any conditions necessitating antibiotic premedication for dental appointment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Interleukin 18. Timepoint: At the time of sampling. Method of measurement: ELISA kit.

Secondary

MeasureTime frame
Interleukin 18. Timepoint: Six weeks after sampling. Method of measurement: ELISA kit.;Bleeding on probing. Timepoint: At the time of sampling. Method of measurement: By periodontal probe.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026