Diadetic polyneuropathy. Type 2 diabetes mellitus with diabetic autonomic (poly)neuropathy
Conditions
Interventions
Intervention 1: Intervention group: Supplement that made of nano mucosal curcumin, an effective ingredient in turmeric, is prepared in the form of gelatin capsules of 80 milligrams from the Minoo Ph
Treatment - Drugs
Placebo
Intervention group: Supplement that made of nano mucosal curcumin, an effective ingredient in turmeric, is prepared in the form of gelatin capsules of 80 milligrams from the Minoo Pharmaceutical Com
Control group: Placebo, which consists of all drug formulation components except the effective curcumin agent, is prepared in the form of gel capsules of 80 mg from Minoo Pharmaceutical Company. A 80
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age between 30 to 60 years old desiration to participate in the study Body mass index between25 - 39.9 Non-insulin diabetic patients type 2 Detection of mild sensorimotor polyneuropathy by using the Toronto questionnaire (score 6-8)
Exclusion criteria
Exclusion criteria: Follow a special diet during last month Sensitivity to curcumin Pregnancy and lactation Eat any nutritional supplement, vitamin and mineral supplement last month History of gastrointestinal ulcer and bile duct There are neuropathies other than the sensory-motor polyneuropathy diabetic diagnosed by a neurologist Take gabapentin and any medication Diseases diagnosed, such as cancer, liver, kidney, autoimmune diseases, inflammatory, thyroid and nervous and cardiovascular diseases, and drug use associated with these diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The severity of neuropathy in the Toronto questionnaire. Timepoint: Before the intervention, After intevention. Method of measurement: Toronto questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting Blood Sugar. Timepoint: Before the intervention, After the intervention. Method of measurement: KIT.;Blood sugar 2 hour after meal. Timepoint: Before the intervention, After the intervention. Method of measurement: KIT.;HBA1C. Timepoint: Before the intervention, After the intervention. Method of measurement: KIT. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSara Asadi
Tehran University of Medical Sciences
Outcome results
None listed