Comparison effect of religious cognitive- behavioral therapy, classic cognitive behavioral therapy and Sertraline on anxiety, depression, related bio markers and quality of life in post coronary artery bypass surgery Patients

Comparison effect of religious cognitive- behavioral therapy, classic cognitive behavioral therapy and Sertraline on anxiety, depression, related bio markers and quality of life in post coronary artery bypass surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201404122898N5

Enrollment

200

Registered

2014-05-24

Start date

2014-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Depression, related biomarkers, Quality of life. Organic anxiety disorder,Depressive episode

Interventions

Intervention 1: Religious Cognitive Behavioral Therapy(intervention group ) 12 one hour psychological session and usual treatment. Intervention 2: Classic Cognitive Behavioral (intervention group )

Behavior

Treatment - Drugs

Religious Cognitive Behavioral Therapy(intervention group ) 12 one hour psychological session and usual treatment

Classic Cognitive Behavioral (intervention group ) 12 one hour psychological session and usual treatment

Sertralin (intervention group)25-200 mg for 3 month and usual treatment

usual treatment( Control group) treatment following heart surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The inclusion criteria include first-time coronary artery bypass, age of less than 65 years, and four weeks passing from their surgery. In addition, they shouldn’t have some mental disorders such as schizophrenia, bipolar disorder, and serious thoughts of suicide according to clinical interview (DSM-IV) that will be done by a psychiatrist. Obtaining the score of 8 or more in depression and anxiety based on HADS questionnaire. They shouldn’t suffer from mental or physical disease that prevents them from taking part in the therapy meetings. They should be able to communicate and speak in Farsi with, at least, junior high school education level .They should get the score of 25 and more in the Golriz and Baraheni’s religious attitude measure questionnaire.The exclusion criteria include: patients who receive Sertraline or other anti anxiety and anti depression drugs, patients who have previously attended the religious cognitive-behavioral therapy and classic cognitive-behavioral therapy courses.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Anxiety. Timepoint: Before intervention ,3,6,9 and 12 month after intervention. Method of measurement: Hospital Anxiety Deprestion Questionnaire ( HADS ).;Depression. Timepoint: Before intervention ,3,6,9 and 12 month after intervention. Method of measurement: Hospital Anxiety Deprestion Questionnaire (HADS ).	—

Secondary

Measure	Time frame
Improving the quality of life. Timepoint: Before intervention ,3,6,9 and 12 month after intervention. Method of measurement: SF-36 questionnair.;To become normal level of biomarkers( ?L6 ??L10 ? DHEA ?cortisol ? TNFa). Timepoint: before intervention ,3and 12 month after intervention. Method of measurement: ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Hamzeh Hosseini

Mazandaran University of Medical Sciences

shhosseini@mazums.ac.ir+98 15 1328 3886

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026