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The effect of Granisetron on pain of Propofol injection

Randomized double-blinded clinical trial: The effect of Granisetron on pain of Propofol injection in patients candidate for elective laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201404095175N12
Enrollment
30
Registered
2014-05-08
Start date
2014-04-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Relation between elective laparoscopic cholecystectomy pain Propofol injection in patients candidate for and Granisetron.

Interventions

Intervention 1: Control group (30 hands) which receive normal saline before Propofol injection. Intervention 2: Intervention group (30 hands) which receive Granisetron before Propofol injection.
Placebo
Prevention
Control group (30 hands) which receive normal saline before Propofol injection.
Intervention group (30 hands) which receive Granisetron before Propofol injection.

Sponsors

Tehran University of Medical Sciences and Health Services
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Ages between 20 and 50; ASA class 1, 2; Candidate for elective laparoscopic cholecystectomy Exclusion criteria: Past medical history of neurological disease; Chronic pain syndrome; Thrombophlebitis; Advanced systemic disease such as advanced diabetes; Any vascular disease; Any contraindication for Granisetron or Propofol injection

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: During injection. Method of measurement: Numeric Rating Scale mentioned by the patient.

Secondary

MeasureTime frame
Postoperative Nausea and Vomiting. Timepoint: In the recovery room. Method of measurement: Nausea and vomiting expressed by the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Movafegh

Tehran University of Medical Sciences, Anesthesiology Department

movafegh@sina.tums.ac.ir+98 21 8490 2397

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026