Epidural Hematoma. Epidural haemorrhage
Conditions
Interventions
Intervention 1: Ampul Tranexamic Acid,1 g as loading dose and then 1 g every 8 Hours in intervention group for two days. Intervention 2: In the control group at two days after the trauma, Tranexam
Treatment - Drugs
Treatment - Other
Ampul Tranexamic Acid,1 g as loading dose and then 1 g every 8 Hours in intervention group for two days
In the control group at two days after the trauma, Tranexamic Acid or placebo was not used.
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Head trauma; GCS=15; Epidural hematoma with maximum diameter of 1 cm; Age 18-75 years old; Informed consent to participate in research Exclusion criteria: GCS less than or equal to 13; Require surgery to evacuate the hematoma; History of anticoagulation therapy; History of head trauma; Occipital hematoma; Multiple trauma; Mid line shift; History of internal disease; age under 18 and older than 75 years old; During lactation and pregnancy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maintain or reduce of Epidural Hematoma diameter after intervention. Timepoint: Before intervention and 48 hours after intervention. Method of measurement: Brain CT Scan and measurment of the maximum diameter of the Epidural Hematoma with Millimetrs.;The rate of change of level of consciousness. Timepoint: At admission and 48 hours after intervention. Method of measurement: Glasgow Coma Score (GCS).;The approximate volume of epidural hematoma. Timepoint: At admission and 48 hours after intervention. Method of measurement: Brain CT Scan and measurment of the maximum volume of the Epidural Hematoma with Milliliters. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzad Mohamadzade, MD
Tabriz University of Medical Sciences
Outcome results
None listed