Evaluation of mizoprostol tablet and mefenamic acid capsule's effect on reducing menstrual bleeding

Evaluation of mizoprostol tablet and mefenamic acid capsule's effect on reducing menstrual bleeding in patients suffering from menorrhagia in Imam Khomeini hospital in 2014.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014040912790N2

Enrollment

Registered

2014-07-12

Start date

2014-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menorrhagia. Excessive, frequent and irregular menstruation

Interventions

Intervention 1: Blood loss is calculated after first menstrual period. Then misoprostol tablet is prescribed for patients so that after second menstrual period, 3 misoprostol 200 µg tablets are used f

Treatment - Drugs

Blood loss is calculated after first menstrual period. Then misoprostol tablet is prescribed for patients so that after second menstrual period, 3 misoprostol 200 µg tablets are used for 3 days. PBAC

Blood loss is calculated after first menstrual period. Then mefenamic acid capsule is prescribed for patients so that after second menstrual period, 3 mefenamic acid 250mg capsules are used for 3 days

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: * Inclusion criteria: women with chief complaint of menorrhagia admitted to the clinic * Exclusion criteria: Presence of contraindications to medications Inability to using medications Presence of ovarian masses or endometrial hyperplasia Presence of systemic disorders such as cardio vascular, hepatic or metabolic diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood loss. Timepoint: First menstruation period - Second Menstruation period. Method of measurement: pictorial blood assesment charts (PBAC).	—

Secondary

Measure	Time frame
Hemoglobin. Timepoint: First menstrual period - Second menstrual period. Method of measurement: Lab test (gr/dL).;Dysmenorrhea. Timepoint: First menstrual period - Second menstrual period. Method of measurement: Asking patient (Score 1-10).;Clot discharge. Timepoint: First menstrual period - Second menstrual period. Method of measurement: Asking patient (Yes/No).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Aref Abedi

Tehran University of Medical Sciences

ab.aref1385@gmail.com+98 912 792 0721

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026