Chemoradiation-induced mucositis. Other and unspecified lesions of oral mucosa
Conditions
Interventions
Intervention 1: Intervention group: The patients will receive laser therapy for 5 successive days with wave length of 630 nanometers, power of 30 mw and dose of 5 j/cm2. The radiation will target 10 s
Prevention
Intervention group: The patients will receive laser therapy for 5 successive days with wave length of 630 nanometers, power of 30 mw and dose of 5 j/cm2. The radiation will target 10 spots about 8mm i
Control group: In the laser off group, laser therapy with off device will be followed.
Sponsors
Vice chancellor for research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
12 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: The patients receiving radiotherapy for their oral cavity and salivary glands for the first time in the 12-70 age range with the healthy oral mucosa; patients whose karnofsky performance status is equal or more than 60; life expectancy more than six months; white blood cell more than 1500 and platelets more than 100000; having a written consent from the patient after the necessary explanations by researcher. Exclusion criteria:The patients with the history of chemoradiation, pregnancy, diabetes and light sensitivity.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral mucositis. Timepoint: 15 visits every other day for 30 days. Method of measurement: Examination, inquiry, registration according to WHO mucositis Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Xerostomia. Timepoint: 15 visits every other day for 30 days. Method of measurement: Examination, inquiry, registration according to LENT soma criteria.;Quality of life. Timepoint: Before and one month after intervention. Method of measurement: EORCT-C30 questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLaleh Naseri
Tabriz University of Medical Sciences
Outcome results
None listed