Effect of intravenous vitamin c on post operative pain.

Effect of intravenous vitamin c on post operative pain in uvulopalatopharyngoplasty (uppp) with tonsillectomy.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201404055764N3

Enrollment

Registered

2015-02-15

Start date

2013-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of vitamin c on uvulopharyngopalatoplasty and tonsillectomy pain. Other and unspecified general anaesthetics

Interventions

Intervention 1: During the first 30 minute after the beginning of the surgery, patients received infusion of 5ml normal salin in 500 ml ringer. Intervention 2: During the first 30 minute after the beg

Prevention

During the first 30 minute after the beginning of the surgery, patients received infusion of 5ml normal salin in 500 ml ringer

During the first 30 minute after the beginning of the surgery, patients received infusion of 3 gr vitamin c in 500 ml ringer.

Eligibility

Sex/Gender

All

Age

25 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 25-50 years; both male and female; BMI<35; American Society of Anesthesia (ASA) physical status I or II; underwent uvulopharyngopalatoplasty with tonsillectomy. Exclution criteria: mental retardation; epilepsy; chronic pain; liver or renal disease; drug abuse and drug allergy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post operative pain. Timepoint: Recovery room, 6, 12 and 24 hours post operation. Method of measurement: VAS score.	—

Secondary

Measure	Time frame
Systolic, Diastolic and Mean blood pressure. Timepoint: Before and during anesthesia, 0,15, 30 and 60 minute after extubation. Method of measurement: mm Hg by Automatic non invasive blood pressure.;Heart rate. Timepoint: Before and during anesthesia, 0,15, 30 and 60 minute after extubation. Method of measurement: Before and during anesthesia, 0,15, 30 and 60 minute after extubation.;Time of the first analgesic request. Timepoint: Hours postoperation. Method of measurement: Recovery room and ward.	—

Measure

Time frame

Systolic, Diastolic and Mean blood pressure. Timepoint: Before and during anesthesia, 0,15, 30 and 60 minute after extubation. Method of measurement: mm Hg by Automatic non invasive blood pressure.;Heart rate. Timepoint: Before and during anesthesia, 0,15, 30 and 60 minute after extubation. Method of measurement: Before and during anesthesia, 0,15, 30 and 60 minute after extubation.;Time of the first analgesic request. Timepoint: Hours postoperation. Method of measurement: Recovery room and ward.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ayatollahi Vida

Shahid Sadoughi Medical sciences university

ayatt.vida@ssu.ac.ir? ayati.vida @yahoo.com+98 35 3822 4001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026