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Comparison of the analgesic effect of magnesium and Tramadol after local anesthesia of upper extremity.

Comparison of the Efficacy of Magnesium sulfate and Tramadol as an adjunct to the Intravenous Regional Block for Controlling Postoperative Pain Following Upper Extremity Surgeries.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014040511662N6
Enrollment
69
Registered
2014-05-23
Start date
2014-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Postoperative Pain. Acute pain

Interventions

Intervention 1: Control group: 10 cc saline in the 10 ml syringe will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc syringe. Intervention 2: Int
Treatment - Drugs
Control group: 10 cc saline in the 10 ml syringe will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc syringe
Interventional group 1: 1.5 gram magnesium sulfate diluted with saline to a volume of 10 cc will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc sy
Interventional group 2 : 100 miligram tramadol diluted with saline to a volume of 10 cc will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc syring

Sponsors

Vice-Chancellery of Research and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 69 patients 15-65 years old with ASA 1&2candidates for elective hand and forearm surgery or due to trauma. Exclusion criteria: History of drug abuse; History of allergies to drugs such as local anesthetics or opioid; History of: liver diseases; cardiovascular disease; renal failure; sickle cell anemia; Raynaud's disease; coagulopathy; G6PD deficiency; seizures.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Postoperative pain intensity. Timepoint: Every hour for 6 hours and then every 4 hours for 24 hours after surgery. Method of measurement: Visual Anlouge Scale.

Secondary

MeasureTime frame
Nausea and Vomiting. Timepoint: Every one hour during first postoperative 24 hr. Method of measurement: Nausea is defined as urge to vomiting without ejection ofof the contents of the stomach through the mouth, Vomiting is defined asto eject of the contents of the stomach through the mouth, usually in a series of involuntary spasmic movements.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ali Sahmeddini

Shiraz University Of Medical Sciences

sahmeddini@sums.ac.ir+98 71 1647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026