The effects of topical atorvastatine (2%) for post-hemorrhoidectomy pain relief and wound healing

Comparison the effects of topical Atorvastatine (2%) with placebo for post-hemorrhoidectomy pain relief and wound healing

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201404013014N8

Enrollment

Registered

2014-10-12

Start date

2014-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Excisional hemorrhoidectomy. External haemorrhoids with other complications

Interventions

Intervention 1: Intervention1: Topical atorvastatine (2%) BID for two weeks. each dose 1cm. Intervention 2: Intervention 2: Placebo, BID for two weeks, each dose 1cm.

Treatment - Drugs

Intervention1: Topical atorvastatine (2%) BID for two weeks. each dose 1cm.

Intervention 2: Placebo, BID for two weeks, each dose 1cm

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Patients who had hemorroidectomy surgery between 18-65 years old? Exclusion criteria:Patients with hypersensivity to atorvastatine ? and those who develop myopathy, renal falier or ulcer size

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Each week for 2 weeks then each month for 2 month. Method of measurement: Visual Analog Scale(VAS).	—

Secondary

Measure	Time frame
Itching. Timepoint: Once monthly for two month. Method of measurement: 5D.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaliheh Hamidian

Mazandaran University of Medical Sciences, Vice chancellor for research

maliheh.hamidian@yahoo.com+98 15 1311 0267

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 1, 2026