Black Seed Oil effect on dysmenorrhea

Clinical trial comparing topical application of Black Seed Oil and placebo on primary dysmenorrheal and premenstrual syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014033117109N1

Enrollment

140

Registered

2015-11-29

Start date

2013-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorder-menstural. Excessive, frequent and irregular menstruation

Interventions

Intervention 1: Intervention group 1: The topical application Baryj Essence Pharmaceutical Company Black Seed Oil contains 30 to 40 percent oil

Linolenic Acid 55%, 2-1 drops will use on the Fontanel area for 30 seconds to two minutes with gently massage. Finding Fontanel area: each person will open her hand completely and put her little fing

Treatment - Drugs

Placebo

Intervention group 1: The topical application Baryj Essence Pharmaceutical Company Black Seed Oil contains 30 to 40 percent oil

Linolenic Acid 55%, 2-1 drops will use on the Fontanel area for 30 seconds to two minutes with gently massage. Finding Fontanel area: each person will open her hand completely and put her little fin

Intervention group 2: The topical application liquid vegetable Oil 2-1 drops on the Fontanel area about 30 seconds to two minutes with gently massage. Finding Fontanel area: each person will open he

Eligibility

Sex/Gender

Female

Age

18 Years to 24 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria consist of: being 15-45 years old; having regular menstrual cycle; severe or moderate menstrual pain; three days maximum duration of pain; at least 3 years of menarche; no medications or herbal pain relief not being; affected by depression or anxiety; not having an acute or chronic disease; not taking medicines or supplements and not having regular exercise The exclusion criteria consist of: pregnancy; willingness to use hormonal contraceptive methods or taking any hormonal treatment; not taking the drug or not filling out the forms regularly; and unwillingness to continue the treatment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain intensity. Timepoint: pre intervention and minimal three period after intervention. Method of measurement: Prospective Record of the Impact and Severity of Menstrual Symptoms (PRISM).;Premenstural syndrom symptoms. Timepoint: Befor intervention and after three menstural periods intervention. Method of measurement: Cox Menstrual Symptom Scale questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEzat Samadipour

Sabzevar University of Medicine Sciences

samadipe@medsab.ac+98 514446070

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026