Condition 1: cervical ripening. Condition 2: induction of labor. Condition 3: medical induction of labour. Condition 4: Delivery. Maternal care related to the fetus and amniotic cavity and possible delivery problems Complications of labour and delivery. Failed medical induction of labour Delivery
Conditions
Interventions
Intervention 1: administration of oral titrated solution of misoprostol. 200 microgram misoprostol will be solved in 200 mili liter water, and 20 cc of this solution will be prescribed every 2 hours
Treatment - Drugs
administration of oral titrated solution of misoprostol. 200 microgram misoprostol will be solved in 200 mili liter water, and 20 cc of this solution will be prescribed every 2 hours. ( maximum 60 m
infusion of 2.5 mili units oxitocine per minute that will be doubled every 15 minutes. Maximum dose of oxitocine is 60 mili units per minute.
Sponsors
Vice chancellor for research ,Iran University of Medical Sciences.
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age between 20-40 year old; reliable gestational age between 40-42 weeks; singleton pregnancy with cephalic presentation; BISHOP Score of more than 5; favorable pelvis. Exclusion criteria: parity of more than 3, blood pressure equal or more than 160/110 mmHg; abnormal NST and any sign of fetal distress; urine protein of more than 2 gram in 24 hours; suspicious for HELLP syndrome; poly hydramnios; probable macrosomia; any vaginal bleeding; history of any surgery on uterus; prostaglandin use during present pregnancy and beginning of spontaneous uterine contractions.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of deliveries during the first 24 hours. Timepoint: 24 hours. Method of measurement: Data sheets. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rout of delivery. Timepoint: ---. Method of measurement: data sheets.;Uterine hyperstimulation. Timepoint: every 30 minutes. Method of measurement: monitoring of uterine contractions- tocography.;Fetal distress. Timepoint: every 15 minutes. Method of measurement: fetal heart rate monitoring with tococardiography.;Neonatal Apgar Score. Timepoint: minute 1 and 5. Method of measurement: data sheets.;Number of deliveries during 6-12-18 hours from the beginning of induction. Timepoint: 6-12-18 hours from the beginning of induction. Method of measurement: data sheets.;Duration of stage 1 , 2 and 3 of labor. Timepoint: end of stage 1 , 2 and 3 of labor. Method of measurement: data sheets.;Interval between the beginning of induction up to the beginning of suitable contractions( 3 forceful contractions during 10 minutes). Timepoint: every 30 minutes. Method of measurement: data sheets.;Indications for cesarean deliveries. Timepoint: during cesarean deliveries. Method of measurement: data sheets.;NICU admission. Timepoint: After birth up to discharge. Method of measurement: data sheets.;Duration of hospital stay for mother and baby. Timepoint: admission , discharge. Method of measurement: data sheets. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Kashanian
Iran University of Medical Sciences
Outcome results
None listed