Spinal cord injury. Injury of spinal cord, level unspecified
Conditions
Interventions
Intervention 1: Each of participant in case-group will be received Atorvastatin 20mg orally every 12 hours. Intervention 2: In the control group, each patient will be received a placebo tablets orall
Treatment - Drugs
Placebo
Each of participant in case-group will be received Atorvastatin 20mg orally every 12 hours.
In the control group, each patient will be received a placebo tablets orally every 12 hours. These capsules have similar shape, color, weight of atorvastatin ones.
Sponsors
Vice Chancellor for research of Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Age: 18-70 years; 2. Weight: 60-80kg; 3. Informed consent; 4. Matched clinical and imaging findings; 5.C4 to L2 vertebral fractures; 6. Frankel Impairment Scale level A, B or C Exclusion criteria: 1. Pregnancy; 2. Lactation; 3. History of depression; 4. History of seizure; 5. History of diabetes, hepatic disorder or cardiovascular disease; 6. Aphasia or visual loss; 7.Unable to receive atorvastatin orally
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lumbar back pain. Timepoint: Primary, 6 weeks and 6 months following end of treatment. Method of measurement: V.A.S (visual analog scale).;Sensory and motor condition. Timepoint: Primary, 6 weeks and months following treatment. Method of measurement: Frankel classification. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hepatic Injury. Timepoint: Primary, 6 weeks and 6 months following treatment. Method of measurement: Liver Function Tests. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed