Melasma. Melasma
Conditions
Interventions
Intervention 1: Control group: hidroqinone cream 2%, one time/day on the lesion of one side of face. Intervention 2: Intervention group: liposomal tranexamic acid cream 1 time/day on the lesion of one
Treatment - Drugs
Control group: hidroqinone cream 2%, one time/day on the lesion of one side of face
Intervention group: liposomal tranexamic acid cream 1 time/day on the lesion of one side of face
Sponsors
Research Council of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: clinically diagnosed melisma patients, age more than 18 years old. Exclusion criteria: pregnancy and breast feeding, simultaneous hormonal disease, drug use including anti barbiturate drugs, recent hormonal and corticosteroids treatments, patients who treated by bleaching therapy on the last four months, patients underwent laser during the last six month, patients who don’t refer on follow up periods, any side effects which canceled the treatment.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of pigmentation. Timepoint: Monthly untill the end of 12 weeks. Method of measurement: Melasma Area and Severity Index. | — |
Secondary
| Measure | Time frame |
|---|---|
| Melasma severity. Timepoint: Comparison melasma severity in baseline and terminal of 3 months treatment course. Method of measurement: Melasma Area and Severity Index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAsma Jabari
Mashhad University of Medical Sciences
Outcome results
None listed