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Povidone iodine and topical erythromycin in prevention of ophthalmia neonatorum

Comparing the effects of topical povidone iodine (2.5%), and topical erythromycin in prevention of ophthalmia neonatorum, in Shiraz, in 2014

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014031717034N1
Enrollment
2100
Registered
2014-04-19
Start date
2014-04-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Neonatal chlamydial conjunctivitis and neonatal conjunctivitis NOS. Condition 2: Neonatal gonococcal conjunctivitis. Neonatal chlamydial conjunctivitis. Ophthalmia neonatorum NOS. Gonococcal conjunctivitis.

Interventions

Intervention 1: Neonates with no eye abnormalities or infection are divided to two groups. Group 1 receives topical erythromycin at the time of birth. At first 24 hours, 3-7 and 7-10 days later patien
Prevention
Neonates with no eye abnormalities or infection are divided to two groups. Group 1 receives topical erythromycin at the time of birth. At first 24 hours, 3-7 and 7-10 days later patients are visited f
Neonates with no eye abnormalities or infection are divided to two groups. Group 2 receives topical povidone iodine at the time of birth. At first 24 hours, 3-7 and 7-10 days later patients are visite
Neonates with no eye abnormalities or infection are divided to two groups. Group 3 (control) receives distilled water at the time of birth. At first 24 hours, 3-7 and 7-10 days later patients are visi

Sponsors

Vice chancellor of research of Shiraz university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Months

Inclusion criteria

Inclusion criteria: Inclusion criteria: mother's consent. Exclusion criteria: Ocular malformations; Antibiotic usage by mother in the last week of pregnancy; Mothers can’t bring the neonate to hospital in case of conjunctivitis; Mothers with current gonococcal or chlamydial infection.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Presence or absence of conjunctivitis. Timepoint: 3 Occasions: After 24 hours, days 3-7 and days 7-10. Method of measurement: History and physical exam.

Secondary

MeasureTime frame
Cultured microorganism. Timepoint: When conjunctivitis detected. Method of measurement: Culture.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Haghbin

Shiraz university of medical sciences

Hoshaq@yahoo.com+98 71 1648 6731

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026