Premenstrual syndrome. Premenstrual tension syndrome
Conditions
Interventions
Intervention 1: The first intervention groups will receive only Lemon balm 500 mg capsules twice daily. Intervention 2: The second intervantion group will recieve Lemon balm plus Nepeta menthoides 50
Treatment - Drugs
The first intervention groups will receive only Lemon balm 500 mg capsules twice daily.
The second intervantion group will recieve Lemon balm plus Nepeta menthoides 500 mg capsules twice daily.
The control group will recieve 500 mg placebo capsules twice daily.
Sponsors
Vice chancellor for research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Aged 18 years and older; Having regular menstrual cycles between 21-35 days; Having a normal BMI (18.5-25) ; Having symptoms in the second half of the cycle; Having symptoms within two cycles before intervention; Having a phone number to follow up; Having tendency to participate in the study Exclusion criteria: Having depression based on the Beck questionnaire; History of specific diseases (epilepsy, digestive, cardio - vascular, renal, neuro-endocrine) according to the self-reported; Taking an antidepressant, anticonvulsant or herbal, vitamins, hormones drugs in the past 3 months; Drinking alcohol and smoking hookah; Incidence of a stressful incident in the past 6 months: Parental divorce, Death of first degree relatives and etc.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity of Premenstural syndrom symptoms. Timepoint: Two cycles Before intervention, 1, 2 cycles during intervention. Method of measurement: DRSP questionnaire.;Quality of life. Timepoint: Before and at the end of second cycle after intervention. Method of measurement: Quality of life questionnaire-SF-36. | — |
Secondary
| Measure | Time frame |
|---|---|
| Amount of menstrual bleeding. Timepoint: Before intervention, first and second cycles during intervention. Method of measurement: Higham chart.;Statisfaction from tratment. Timepoint: After the end of intervention. Method of measurement: Questionnaire.;Frequency of adverse events. Timepoint: During intervention. Method of measurement: Checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSolmaz Ghanbari Homayi
Tabriz University of Medical Sciences, Nursing & Midwifery Faculty
Outcome results
None listed