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Comparison of the effect of two regimens of metformin and insulin on glucose tolerance test

Comparison of pregnancy outcome and glycemic control between insulin versus insulin plus metformin in management of gestational diabetes.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140317017035N5
Enrollment
80
Registered
2020-05-04
Start date
2018-07-09
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational Diabetes. Gestational diabetes mellitus in pregnancy

Interventions

Intervention 1: Intervention group: In first group of intervention, if the blood suger is not controlled with diet. Initially, insulin will be started at 0.5_1 unit per kg, and then if it need, more

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Single-pregnancy Gestational age 20-34 weeks FBS is higher than 100 mg/dL Age range 18 to 40 years

Exclusion criteria

Exclusion criteria: Diagnosis of pre-pregnancy diabetes, presence of metabolic disorders in the patient Need to start treatment with insulin in oral treatment patients Dissatisfied to cooperate in the study Metabolic disorder in the patient Gestational Hypertension

Design outcomes

Primary

MeasureTime frame
Control of serum glucose level in pregnant women with gestational diabetes mellitus. Timepoint: On average checked twice at week 36. Method of measurement: Oral Glucose Tolerance Test.;Blood sugar levels. Timepoint: 1 hour after birth. Method of measurement: Glucometer.

Secondary

MeasureTime frame
Neonate weight. Timepoint: After birth. Method of measurement: scale.;Apgar score. Timepoint: First and fifth minutes after birth. Method of measurement: Apgar score scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Ghahartars

Shiraz University of Medical Sciences

Hafez_perina@sums.ac.ir+98 71 3233 2365

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026