constipation. constipation
Conditions
Interventions
Intervention 1: In malva sylvestris group, syrup is given 10cc twice daily,2 hours after breakfast and lunch for 4 weeks. Intervention 2: In placebo group, DW50% syrup approves 10 cc twice daily,2hou
Treatment - Drugs
In malva sylvestris group, syrup is given 10cc twice daily,2 hours after breakfast and lunch for 4 weeks.
In placebo group, DW50% syrup approves 10 cc twice daily,2hours after breakfast and lunch for 4 weeks.
Sponsors
Faculty of Traditional Medicines,Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Men and women aged 18–65 as having at least two or more of the following, during 25% of defecation times: very hard and/or hard stools; sensation of incomplete evacuation; straining at defecation; a need for digital manipulation to facilitate evacuation.These criteria should have been fulfilled for the 3 previous months with symptom onset at least 6 months prior to diagnosis. Exclusion criteria:Men and women 65 years;patients with mentioned criteria & drug-induced constipation, patients suffering from secondary causes of chronic constipation, including endocrine, metabolic, or neurological disorders; patients with a history of gastrointestinal surgery(exception of appandectomy and cholecystectomy); those with a diagnosis of constipation dominant IBS; Patients with alarming symptoms (fever, recent weight loss , and anaemia)& constipation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Defecation rate per week on average. Timepoint: before interventing &2,4 weeks aftertreatment. Method of measurement: ROME III questionnaire.;Hard stools. Timepoint: before interventing & 2,4 weeks aftertreatment. Method of measurement: ROME III questionnaire& Bristol stool form scale.;Need for digital manipulation to facilitate evacuation. Timepoint: before interventing & 2,4 weeks aftertreatment. Method of measurement: ROME III questionnaire.;Sensation of blockage. Timepoint: before interventing & 2,4 weeks aftertreatment. Method of measurement: ROME III questionnaire.;Straining of defecation. Timepoint: before interventing & 2,4 weeks aftertreatment. Method of measurement: ROME III questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rarely dyspepcia. Timepoint: every time patient reports. Method of measurement: patient report. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahin Elsagh
Faculty of Traditional Medicines ,Iran University of Medical Science
Outcome results
None listed