Effect of (aqueous-alcoholic) extracts of Zataria multiflora and carvacerol on symptoms,and respiratory function on chemical war victims

The effect of aqueous-alcoholic extracts of Zataria multiflora and carvacerol on respiratory symptoms, pulmonary function tests and serum inflammatory mediators in chemical war victims

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014031617020N1

Enrollment

Registered

2016-03-04

Start date

2015-07-29

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chemical war victims with respiratory symptoms. Chronic respiratory conditions due to chemicals, gases, fumes and vapours

Interventions

Intervention 1: Group 3: Patients treated with carvacrol 0.42 mg/kg three time daily for 2 months. Intervention 2: Group 4: Patients treated with placebo three time daily for 2 months. Intervention 3:

Treatment - Drugs

Group 3: Patients treated with carvacrol 0.42 mg/kg three time daily for 2 months

Group 4: Patients treated with placebo three time daily for 2 months

Group 1: Patients treated with aqueous-alcoholic extracts 1.5 mg/kg three time daily for 2 months

Group 2: Patients treated with aqueous-alcoholic extracts 3 mg/kg three time daily for 2 months

Eligibility

Sex/Gender

Male

Age

45 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: The pationts expoused to sulfur mustard. Exclusion criteria: The pationts should not have any cardiovascolar disorders

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Respiratory symptoms. Timepoint: Baseline, one month and 2 months after treatment. Method of measurement: Check list and examination.;Pulmonary function test. Timepoint: Baseline, one month and 2 months after treatment. Method of measurement: Spirometry.	—

Secondary

Measure	Time frame
Serum inflammatory mediators level. Timepoint: Baseline, one month and 2 months after treatment. Method of measurement: By elisa kits.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Khazdair

Mashhad University of Medical Sciences

Khazdeirmr921@mums.ac.ir; M.khazdair@yahoo.com+51 38002216

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 4, 2026