Acne Vulgaris. Acne vulgaris
Conditions
Interventions
Intervention 1: Intervention group 1 =the use of gel azithromycin 2% on half of the face 2 times a day for 2 months. Intervention 2: Intervention Group 2 (Control )=the use of gel clindamycin 1% on ha
Treatment - Drugs
Intervention group 1 =the use of gel azithromycin 2% on half of the face 2 times a day for 2 months
Intervention Group 2 (Control )=the use of gel clindamycin 1% on half of the face 2 times a day for 2 months
Sponsors
VICE CHANCELLOR FOR RESEARCH OF ISFAHAN UNIVERSITY OF MEDICAL SCIENCES
Eligibility
Sex/Gender
All
Age
12 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with mild and moderate FDA acne grading system scale , aged 12 to 45 years, both sexes, written informed consent for participation in the study , not receiving topical antibiotics within two weeks and systemic medications that are effective in acne within a month prior to the study, no history of hypersensitivity to any of the studies medications. Exclusion criteria: pregnancy or lactation, medical allergy or side effects, non- cooperation or lack of satisfactory treatment, the need for systemic medication during the study or concomitant use of drugs affecting acne
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of Acne. Timepoint: Beginning of the study design, 4th and 8th weeks of the treatment and 2 months after treatment. Method of measurement: Total count of lesions= TLC and acne severity index = ASI.;Patient satisfaction. Timepoint: 4th and 8th weeks of treatment and 2 months after treatment. Method of measurement: Scale of 10 ratings. | — |
Secondary
| Measure | Time frame |
|---|---|
| Burning and itching. Timepoint: 4th and 8th weeks of treatment and 2 months after treatment. Method of measurement: A scale of 4 ratings.;Erythema. Timepoint: 4th and 8th weeks of treatment and 2 months after treatment. Method of measurement: A scale of 4 ratings.;Dry. Timepoint: 4th and 8th weeks of treatment and two months after treatment. Method of measurement: A scale of 4 ratings.;Desquamation and peeling. Timepoint: 4th and 8th weeks of treatment and 2 months after treatment. Method of measurement: A scale of 4 ratings.;Recurrence. Timepoint: 2 months after treatment. Method of measurement: index of severity of acne=ASI Total lesion count = TLC. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDR. AKRAM BASIRI
ISFAHAN UNIVERSITY OF MEDICAL SCIENCES-DEPARTMENT OF DERMATOLOGY
Outcome results
None listed