Cutaneous Leishmaniasis. Cutaneous Leishmaniasis
Conditions
Interventions
Intervention 1: Intervention group: use of topical liposomal Azithromycin twice daily for 6 weeks. Intervention 2: Control group: injection of intralesional meglumine antimoniate (glucantime) weekly f
Treatment - Drugs
Intervention group: use of topical liposomal Azithromycin twice daily for 6 weeks
Control group: injection of intralesional meglumine antimoniate (glucantime) weekly for 6 weeks
Sponsors
Mashhad University of Medical Sciences, Vice Chancellor for Research
Eligibility
Sex/Gender
All
Age
1 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Presence of cutaneous leishmaniasis with less than 12 weeks of clinical course; Not receive any treatment before Exclusion criteria: Pregnancy; Lactating; Receiving simultanous treatment with other methods during treatment course; Sensitivity or intolerance to Macrolids; History of significance renal; Pulmonary and cardiovascular disease
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lesion improvement. Timepoint: Weekly until 6 weeks. Method of measurement: Measuring the size of induration and ulcer by caliper. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: Weekly. Method of measurement: Clinical evaluation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Pouran layegh
Cutaneous Leishmaniasis Research center, Mashhad University of Medical Sciences
Outcome results
None listed