chronic sinusitis. J32.0, J32.1
Conditions
Interventions
Intervention 1: Group 1: Cap 250 mg tranexamic acid 1 gr orally 2 hours before surgery. Intervention 2: Group 2: Tab Prednisolone 50 mg with doses 1 mg / kg per day orally for 5 days before surgery. I
Treatment - Drugs
Group 1: Cap 250 mg tranexamic acid 1 gr orally 2 hours before surgery
Group 2: Tab Prednisolone 50 mg with doses 1 mg / kg per day orally for 5 days before surgery
Group 3: will not receive any drug
Sponsors
Vice chancellor for research, Kashan University of Medical sciences
Eligibility
Sex/Gender
All
Age
15 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with ASA class 1 and 2; aged between 15 to 75 year-old; hemoglobin level more than 10 mg/dl. Exclusion criteria: sensitivity or contraindication of use corticosteroids and tranexamic acid; history of clotting disorders; previous operation at the same region; uncontrolled hypertension; consuming of corticosteroids in last 2 months .
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative blood loss volume. Timepoint: At the end of surgery. Method of measurement: The amount of the accumulated blood volume in the suction and the surgery field.;Quality of the surgery field. Timepoint: During surgery. Method of measurement: Endoscopy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative intravenous fluid intake. Timepoint: Every 30 minutes during surgery. Method of measurement: Administered fluid volume. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNasim Valizadeh
Kashan university of medical sciences
Outcome results
None listed