Comparison of propofol and isoflurane on intraocular pressure changes

Comparison of two anesthesia techniques, Isoflurane versus Propofol, on Intraocular Pressure (IOP) changes during prone position in laminectomy surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140310016917N7

Enrollment

Registered

2018-11-30

Start date

2018-12-01

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candidates for laminectomy.

Interventions

Intervention 1: Intervention group: Anesthesia will be done with Isoflurane USP and N2O. In Premedication stage Remifentanyl 0.5 µg/kg and Midazolam 2 mg will be used intravenously. In Induction st

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Candidates for laminectomy

Exclusion criteria

Exclusion criteria: Eye disease history Prohibition pron position Prohibition of the use of toneupen No use of any eye drops No history of glaucoma and eye hypertension

Design outcomes

Primary

Measure	Time frame
Changes in intraocular pressure. Timepoint: In 5 turns:1. The patient supine position before induction of anesthesia (baseline phase) 2.Anesthesia (in the first supine position) 3.Anesthesia (in the first prone position) 4. End-stage surgery(in the second prone position) 5.Supine final step before awakening. Method of measurement: With toneupen device, Richter Model.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Ashraf

Rasht University of Medical Sciences

aliashraf@gums.ac.ir+98 13 3332 2250

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026