The effects of local tranexamic acid on dacryocystorhinostomy hemorrhage

The effects of local tranexamic acid on reducing of intra and post external dacryocystorhinostomy hemorrhage in patients with primary acquired nasolacrimal duct abstruction

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140310016917N6

Enrollment

126

Registered

2018-10-16

Start date

2018-09-06

Completion date

Unknown

Last updated

2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital and secondary stenosis and stricture of lacrimal duct. Congenital stenosis and stricture of lacrimal duct

Interventions

Intervention 1: Intervention group: 3.5ml Bupicaine 5%, 4ml Lidocain 2%, 0.1ml Aderenalin 1/100000,2.5ml Tranexamic Acid. Intervention 2: Control group: 3.5ml Bupicaine 5%, 4ml Lidocain 2%, 0.1ml Ader

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with primary and acquired obstruction of the nasolacrimal duct undergo surgery for dacryosisturinostomy under local anesthesia

Exclusion criteria

Exclusion criteria: Coagulation disorders Age less than 50 years Surgery with general anesthesia Allergic reaction to lidocaine or tranexamic acid Uncontrolled hypertension History of anticoagulation History of thromboembolic disease and thrombophilia Hemoglobin is less than 10

Design outcomes

Primary

Measure	Time frame
Reduced bleeding during surgery. Timepoint: During and after the surgery. Method of measurement: Suctioned blood volume and quality of the surgical field surgeon.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Ashraf

Rasht University of Medical Sciences

aliashraf@gums.ac.ir+98 13 3332 2250

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026