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Effect of administration GNRH agonist(Triptrolin) on clinical pregnancy in ART

Comparison administration single dose GNRH agonist(Triptrolin) with placebo in the luteal phase on clinical pregnancy rate in ART cycle in the infertile women.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014030916912N1
Enrollment
328
Registered
2014-06-26
Start date
2014-05-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

INFERTILITY. Female infertility associated with male factors

Interventions

Intervention 1: Three days after embryo transfer ,0.1 mg(1ml) triptrolin subcutaneous was injected for patients in intervention group. Intervention 2: Patients in control group received 1ml normal sa
Treatment - Drugs
Three days after embryo transfer ,0.1 mg(1ml) triptrolin subcutaneous was injected for patients in intervention group.
Patients in control group received 1ml normal saline subcutaneous injection three days after embryo transfer.

Sponsors

Vice Chancellor for Research , Tehran University of Medical Sceince
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
16 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria :couples undergoing ART with their own gametes ; good and high responder women;women age less than 40,FSH level less than 10 mIU/ml on third day of mense ,AMH more than 1.1 ng/ml; couples having at least one embryo available for transfer. Exclusion criteria:couples undergoing ART with donation gamate;azospermia;poor responder women: women age more than 40 ,FSH level more than 10 mIU/ml on third day of mense,AMH less than 1.1 ng/ml and less than 4 f0llicles in previous ART cycle.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy. Timepoint: eight week after intervention. Method of measurement: vaginal sonography.

Secondary

MeasureTime frame
Implantation rate. Timepoint: Ten week after intervention. Method of measurement: vaginal sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeedeh Gharahjeh

Tehran University of Medical Sciences

s-gharahgeh@razi.ac.irDr.gharahgeh_1388@yahoo.com+98 21 8490 2421

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026