infertility. Complications of attempted introduction of fertilized ovum following in vitro fertilization
Conditions
Interventions
Intervention 1: Drug Intervention group:Calcitriol tab 0.5microgram daily for 4 weeks. Intervention 2: Control group: placebo administered to patients in this group for 4 weeks.
Treatment - Drugs
Placebo
Drug Intervention group:Calcitriol tab 0.5microgram daily for 4 weeks
Control group: placebo administered to patients in this group for 4 weeks
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Written consent; Lack of bone diseases (disorders); Lack of Kidney (renal) diseases; The absence of endocrine glands' disorders (abnormalities);Absence of chronic digestive disorders (Crohn's, colitis, ulcers, chronic diarrhea); Non-affliction to vitamin D and calcium metabolism disease that their specific effects have proven; Non-use of vitamin D and calcium supplements before entry into the study (oral use in two weeks ago and injection in the last six months); No use (Failure to use) drugs that have significant effects on serum levels of these compounds (vitamin D and calcium), such as antiepliletics (anticonvulsant), diuretics, cardiac drugs, blood pressure medications (drugs), cimetidine, theophilline, cholestyramine; Serum calcium level less than 10/5 g/dl Exclusion criteria: Allergy to Vitamine D, vitamine D malabsorbtion syndrome, renal function disorder (abnormality), afflicted with hypercalcemia or vitamine D toxicity; Stop treatment (teraphy), ovulation stimulation or embryon transfer for any reseon; Afflicted with the disease affecting vitamine D level (renal diseases, endocrine system disorders); Afflicted with the disease affecting immenuty system; Use of drugs (medicine) affecting unction of immenuty system ; Exsposure to UV rays (radiation) subject to (with) medical and remedy (teraphy) purposes; Afflicted with acute diseases recently
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vitamin d level in blood. Timepoint: before starting the process of IVF. Method of measurement: sampling. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed