opioid dependency. Mental and behavioural disorders due to use of opioids
Conditions
Interventions
Intervention 1: In the clonidine group, Patients are given oral clonidine with dose of 3 – 5 microgram/kg, 60 minutes before endotracheal intubation. Intervention 2: in the Fentanyl group, Fentanyl 1
Treatment - Drugs
in the Fentanyl group, Fentanyl 1 microgram/kg is injected intravenously 5 minutes before indotracheal intubation
In the clonidine group, Patients are given oral clonidine with dose of 3 – 5 microgram/kg, 60 minutes before endotracheal intubation.
Sponsors
Vice Chancellor for Research, Gonabad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age range of 18-65 years old? Candidate for elective surgery and those who were in ASA class of 1 and 2? The drug-dependent patients based on our definitions? No history of other addictive materials such as alcohol and psychoactive drugs? ptients should not have any anxiety disorders. Exclusion criteria: Any cardiovascular problems and arrhythmias during intubation? Over once to attempt intubation that may take more than 20 seconds? Any problem during intubation and surgery in which necessary interventions and desired measurements be impossible.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure and diastolic blood pressure. Timepoint: Before intubation, immediately after intubation and 5 minutes after intubation. Method of measurement: Measurement of blood pressure using a mercury sphygmomanometer.;Heart rate. Timepoint: Before intubation, Immediately after intubation and 5 minutes after intubation. Method of measurement: Radial pulse counting with second time. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Reza Talai
15 Khordad Hospital Beydokht
Outcome results
None listed