Effect of folic acid and metformin on inflammatory factors in children with obesity

Effect of folic acid and metformin on inflammatory factors in pediatric obesity

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014030516435N2

Enrollment

Registered

2014-05-10

Start date

2014-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity. Other specified metabolic disorders

Interventions

Intervention 1: The first group will receive folic acid 1mg tablet . Intervention 2: The second group will receive metformin1000mg tablet .

Treatment - Drugs

The first group will receive folic acid 1mg tablet .

The second group will receive metformin1000mg tablet .

Eligibility

Sex/Gender

All

Age

6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: children and adolescents with body mass index greater than or equal to 95th percentile and between the age of 6-12years old Exclusion criteria: obesity due to genetic syndromes; obesity due to endocrine disorders such as hypothyroidism and Cushing; Children under dieting for weight loss; kidney or liver disease; children who use the supplement

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Decrease in insulin sensitivity. Timepoint: Two months later. Method of measurement: Sampling.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026