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Effect of weight loss on inflammatory indicators in obese patients with fatty liver disease

Determine effect of weight loss on serum level of inflammatory cytokines in obese patients with fatty liver disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014030515105N2
Enrollment
40
Registered
2014-03-31
Start date
2013-12-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatty liver. Fatty (change of) liver

Interventions

low calorie diet.
Lifestyle
low calorie diet

Sponsors

Vice chancellor for research, Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ( Diagnosis of fatty liver disease according to increased liver enzymes and report of sonography; Body mass index equal or greater than 30; Agreement to participate in the study; Obedience to regimen) Exclusion criteria: ( Metabolic or systemic inflammatory diseases; Diabetes mellitus; Ongoing use of anti inflammatory, Immunosuppressive or metabolism affecting medications, Weight or appetite loss medications; Pregnancy; Breast feeding; Daily smoking; Disobedience to regimen)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Weight. Timepoint: Before and just after intervention. Method of measurement: Use same scale and according to Kilogram.

Secondary

MeasureTime frame
High sensitivity C- Reactive protein. Timepoint: Before and just after intervention. Method of measurement: Elisa according to Nanogram per mililiter.;Tumor necrosis factor alpha. Timepoint: Before and just after intervention. Method of measurement: Elisa according to Picogram per mililiter.;Interleukin-1beta. Timepoint: Before and just after intervention. Method of measurement: Elisa according to Picogram per mililiter.;Interleukin-6. Timepoint: Before and just after intervention. Method of measurement: Elisa according to Picogram per mililiter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKamal Boostani

Tabriz University of Medical Sciences

Kamal_boostani@yahoo.com+98 41 1336 7473

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026