Thyroid nodule. Disorders of thyroid gland
Conditions
Interventions
Intervention 1: Intervention group:using Levothyroxine with Therapeutic dose of - 1/8 µgr/kg - daily- for six months. Intervention 2: Control group : half to one tablet daily for 6 months.
Treatment - Drugs
Placebo
Intervention group:using Levothyroxine with Therapeutic dose of - 1/8 µgr/kg - daily- for six months
Control group : half to one tablet daily for 6 months
Sponsors
Guilan University of Medical Sciences Vice chancellor for research
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with single nodule or multi nodules ; that has been proved to be benign with FNA. Exclusion criteria: age under 20 and over 60 ; history of hypo and hyperthyroidism ; history of using Levothyroxine or other related drugs to thyroid ; pregnancy ; other diseases ( cardiovascular or liver disease )
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| TSH. Timepoint: before intervention and 6 weeks later and 6 months later. Method of measurement: laboratory kit. | — |
Primary
| Measure | Time frame |
|---|---|
| Thyroid nodule size. Timepoint: begining of assessment - six months later. Method of measurement: Ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSa'eed kalantari
Razi hospital
Outcome results
None listed