Rheumatoid Arthritis. Rheumatoid arthritis, unspecified
Conditions
Interventions
Intervention 1: Intervention Group: Patients that refer to hospital shariatti have interval criteria and will receive CLAs supplement voluntarily and they receive daily 2*1.25gr glycerinated CLAs(50
Treatment - Other
Placebo
Intervention Group: Patients that refer to hospital shariatti have interval criteria and will receive CLAs supplement voluntarily and they receive daily 2*1.25gr glycerinated CLAs(50-50) capsules fo
Control groups: Patients that refer to hospital shariatti have interval criteria and will receive placebo voluntarily and they receive daily 2*1.25gr Sunflower capsules for 3 months.
Sponsors
Vice-chancellor for Research, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 69 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: person with RA diseases as ACR criteria, having RA from 2 years ago; age between 18-69 years; not being pregnant or lactated; not smoking and drink alcohol; haven’t eaten multivitamin or antioxidants supplements from 3 month ago; don't eat lowering blood pressure; don't eat anti pregnancy drugs, exclusion criteria: Changes in diet or physical activity every day; taking less than 80% of supplements given to patients at baseline(the compliance lower than %80); consumption of contraceptives, multivitamins and antioxidant supplements; renal , hepatic , thyroid, parathyroid diseases, cancer, heart. diseases.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Telopeptide C. Timepoint: Before and after the study. Method of measurement: Bleeding and measurment with ELISA.;Osteocalcine. Timepoint: Before and after the study. Method of measurement: Bleeding and measurment with ELISA.;Serum PTH. Timepoint: Before and after the study. Method of measurement: Bleeding and measurment with ELISA.;Serum Calcium. Timepoint: Before and After the study. Method of measurement: Bleeding and measurment with HPLC. | — |
Secondary
| Measure | Time frame |
|---|---|
| Nsaid usage. Timepoint: Before and after study. Method of measurement: Questionnair.;BMI. Timepoint: Before and after study. Method of measurement: Formula. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNaheed Aryaeian
Iran University of Medical Sciences
Outcome results
None listed