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Comparison of hemodynamic changes due to endotracheal intubation with labetalol and remifentanil in severe preeclamptic patients undergoing cesarean delivery with General Anesthesia

Hemodynamic changes due to endotracheal intubation in severe preeclamptic patients during cesarean section with General Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014022810765N5
Enrollment
70
Registered
2014-07-25
Start date
2014-07-02
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

complication of anesthesia.

Interventions

Intervention 1: Patients in group 1 will be received remifentanil 1µg/kg intravenously 2 minute prior to induction of anesthesia. Then rapid sequence induction of anesthesia using thiopental 5 mg/kg
Treatment - Drugs
Patients in group 1 will be received remifentanil 1µg/kg intravenously 2 minute prior to induction of anesthesia. Then rapid sequence induction of anesthesia using thiopental 5 mg/kg and suxamethoni
Patients in group 2 will be received labetalol 0.25 mg/kg intravenously 5 minute prior to induction of anesthesia. Then rapid sequence induction of anesthesia using thiopental 5 mg/kg and suxamethoniu

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
19 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : parturients with severe preeclampsia undergoing cesarean section with general anesthesia; women with ASA class II and III; patient's written informed consent for contribute in study Exclusion criteria: Women with ASA class IV or above; patients with severe asthema; congestive heart failure; arrhythmia; problems with intubation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Blood Pressure. Timepoint: Pre-induction, pre-intubation, and at 1, 3, and 5 min after intubation. Method of measurement: None Invasie BP measure.

Secondary

MeasureTime frame
Heart Rate. Timepoint: Pre-induction, pre-intubation, and at 1, 3, and 5 min after intubation. Method of measurement: ECG Monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Sousan Rasooli

Tabriz University of Medical Sciences

Rasooli_s@yahoo.com+98 41 1553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026