The comparison of the effect of N-acetylcysteine and angiotensin- converting enzyme inhibitors with angiotensin-converting enzyme inhibitors alone to control blood pressure in hypertensive patients

The comparison of the effect of N - acetylcysteine and angiotensin- converting enzyme inhibitors with angiotensin-converting enzyme inhibitors alone to control blood pressure in hypertensive patients referred to Hajar medical hospital

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014022616750N1

Enrollment

126

Registered

2014-04-21

Start date

2014-03-02

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood pressure. Essential (primary) hypertension

Interventions

The first group is to be prescribed NAC with the doses of the 600mg dissolved in 30cc water/12hrs along with ACEI for two months. The second group is to be treated with ACEI alone. During this two m

Treatment - Drugs

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The inclusion criteria: having age of 18 years old or more; systolic blood pressure of 140 mmHg or higher despite of taking ACEI. The people who are afflicted with Cystinuria; has kidney stones especially Cysteine stones; show severe sensitivity to ACEI and NAC and also the patients who need the other antihypertensive drugs besides ACEI to control their blood pressure are to be excluded from the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Before the study, every 5-7 days during the study for two months. Method of measurement: Measured based on mmHg by Mercury barometer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mahmoud Mobasheri

Shahrekord,Medical Sciences University Of

mobasheri@skums.ac.ir+98 38 1334 2414

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026